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Resources › Clinical Evidence › Part 1 of 5

Measured against the hospital reference

INVU’s signals compared with CTG for heart rate and the intrauterine pressure catheter for contractions.

2022
Novel uterine contraction monitoring to enable remote, self-administered nonstress testingSchwartz N, Mhajna M, Moody HL, et al. Am J Obstet Gynecol 2022;226(4):554.e1–12

Against the intrauterine pressure catheter, INVU detected contractions more accurately than TOCO and was not affected by BMI.

Penn Medicine, UAMS
2022
A novel, cardiac-derived algorithm for uterine activity monitoring in a wearable remote deviceMhajna M, Sadeh B, Yagel S, et al. Front Bioeng Biotechnol 2022;10:933612

Uterine activity derived from INVU’s ECG and acoustic signals tracked the intrauterine catheter closely.

Hadassah, Heidelberg, Penn, EVMS
2020
Wireless, remote solution for home fetal and maternal heart rate monitoringMhajna M, Schwartz N, Levit-Rosen L, et al. Am J Obstet Gynecol MFM 2020;2(2):100101

In 147 women, INVU fetal and maternal heart rate agreed closely with CTG (fetal heart rate r = 0.92).

Hadassah, Heidelberg, Penn, EVMS
2019
Comparative performance of INVU™ versus intrauterine pressure catheter (IUPC) in uterine contractions monitoring of pregnant womenClinicalTrials.gov NCT03889405 · completed 2020

Registered comparison of INVU contraction monitoring with the catheter (80 enrolled).

Sponsor: Nuvo
2018
Evaluating the safety of PregSense™ and comparing its performance to CTG in prenatal monitoring of pregnant subjectsClinicalTrials.gov NCT03504189 · completed 2018

Registered pivotal comparison with CTG at sites in Germany, Israel and the US (151 enrolled).

Sponsor: Nuvo

Highlighted papers

what the journals found, in plain language
Sheba Beyond: a hospital unit for high-risk pregnancy, at home — Nuvo cover picture Programme studyFront Digit Health · 2026

Sheba Beyond: a hospital unit for high-risk pregnancy, at home

Sheba Beyond describes how it designed a hybrid hospital-and-home unit for high-risk pregnancy, using INVU by Nuvo for fetal heart tracing at home.

Read the highlight →
Sheba: gestational diabetes care split between home and clinic — Nuvo cover picture Pilot studyIJGO · 2025

Sheba: gestational diabetes care split between home and clinic

Sheba Medical Center ran a hybrid programme for women with gestational diabetes, with INVU for the nonstress test at home.

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What patients said about testing at home — Nuvo cover picture Research letterAJOG MFM · 2024

What patients said about testing at home

Penn researchers asked patients who did their nonstress tests at home with INVU how it went, through weekly surveys and interviews.

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Banner Health: a year of remote NSTs in rural care — Nuvo cover picture Letter to the editorsAJOG · 2024

Banner Health: a year of remote NSTs in rural care

A Banner Health clinician wrote to the journal about a year of remote nonstress testing with INVU in rural care.

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Penn Medicine: high-risk patients did their NSTs at home — Nuvo cover picture Research letterAJOG · 2023

Penn Medicine: high-risk patients did their NSTs at home

At Penn Medicine, 34 patients with high-risk pregnancies enrolled and 29 did their nonstress tests at home with INVU.

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Independent review of the next generation of fetal monitoring — Nuvo cover picture ReviewBMC Pregnancy Childbirth · 2023

Independent review of the next generation of fetal monitoring

An independent review of remote fetal monitoring in the COVID-19 era describes INVU among the new technologies.

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Contraction monitoring more accurate than the standard belt — Nuvo cover picture Validation studyAJOG · 2022

Contraction monitoring more accurate than the standard belt

INVU’s contraction monitoring was tested in 118 women (78 in the validation phase) against the intrauterine pressure catheter, the clinical reference.

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Contractions read from the heart’s own signals — Nuvo cover picture Validation studyFront Bioeng Biotechnol · 2022

Contractions read from the heart’s own signals

INVU derives uterine activity from the mother’s heart signals, electrical and acoustic, rather than from a pressure belt.

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INVU heart-rate readings agreed closely with hospital CTG — Nuvo cover picture Validation studyAJOG MFM · 2020

INVU heart-rate readings agreed closely with hospital CTG

In 147 pregnant women, fetal and maternal heart rates recorded with INVU were compared with standard cardiotocography (CTG).

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Keep exploring

More about INVU™ beyond the published research.

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Email info@nuvocares.com ↗